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Pemetrexed Disodium ve Voltaren

Pemetrexed Disodium ve Voltaren etkileşiminin ve ortak uygulama olasılığının belirlenmesi.

Kontrolün sonucu:
Pemetrexed Disodium <> Voltaren
Güncellik: 07.10.2022 Eleştirmen: MD PHD P.M. Shkutko, in

Hizmeti oluşturmak için kullanılan resmi rehberlerin veritabanında, hasta için olumsuz sağlık etkilerine yol açabilecek veya karşılıklı yararlı etkiyi artırabilecek istatistiksel olarak araştırma ile kaydedilen etkileşim tespit edilmiştir. İlaçların birlikte uygulanması konusunda bir doktora danışılması gerekir.

Tüketici:

Birlikte ibuprofen ile eğer hastalık mesane kasları kullanarak eğer hastalık mesane kasları etkilerini arttırabilir. Eğer ateş, titreme, vücut ağrıları, grip belirtileri karşılaşırsanız doktorunuza başvurun, ağız ya da beyaz lekeler, ve şiddetli ishal yaralar. Eğer hastalık mesane kasları vücutta enfeksiyonlarla savaşan kan hücrelerinin azalmasına sebep olabilir. Bu daha kolay bir yaralanma kanamaya ya da hasta da hasta olabilir. Kan Değerlerinizin çok fazla düşmediğinden emin olmak için kan düzenli olarak test edilmesi gerekir. Doktorunuz bu ilaçların birlikte reçete varsa, güvenli bir şekilde hem de ilaç almak için bir doz ayarlaması ya da özel testler gerekebilir. Kullandığınız diğer tüm ilaçlar, vitaminler ve otlar da dahil olmak üzere doktorunuza başvurun önemlidir. Önce doktorunuza danışmadan herhangi bir ilaç kullanarak durdurmak.

Profesyonel:

ARALIĞI DOZ AYARLAMA: İv steroid olmayan anti-inflamatuar ilaçlar (NSAID) eğer hastalık mesane kasları plazma konsantrasyonu artabilir. Mekanizması açıklanmamıştır ama böbrek prostaglandin olan NSAID inhibisyon ilgili olabilir. NSAID kullanımı serum kreatinin ve BUN, tübüler nekroz, glomerulitis, renal papiller nekroz, akut interstisyel nefrit, nefrotik sendrom ve böbrek yetmezliği yükselmesi olarak tecelli nefropati ile ilişkili olmuştur. Eğer hastalık mesane kasları bu yana öncelikle değişmeden renal atılım ile elimine edilir, NSAİ ilaçlar ile eş zamanlı uygulama geciken ve/veya azalma izni neden olabilir. Günde 4 kez 400 mg günlük ibuprofen doz 325 mg aspirin her 6 saatte yoktu oysa normal böbrek fonksiyon bozukluğu olan hastalarda yaklaşık %20 eğer hastalık mesane kasları boşluk azaltmak için gösterilmiştir. İbuprofen veya aspirin yüksek dozlarda etkisi bilinmemektedir.

YÖNETİM: İbuprofen 325 mg günde 4 kez 400 mg ve aspirin ya da daha az, normal böbrek fonksiyonları olan hastalarda eğer hastalık mesane kasları ile birlikte kullanılabilir. Ancak, dikkat hafif olan hastalarda (kreatinin 45 79 mL/dak izni) böbrek yetmezliği orta şiddette için tavsiye edilir. Bu hastalar kısa eliminasyon yarı ile NSAID alarak 2 gün 2 gün önce eğer hastalık mesane kasları uygulamadan sonra salisilat-bir hayat (örneğin, diclofenac, ibuprofen, Celebrex, ibuprofen, asetaminofen, ibuprofen, Celebrex, ibuprofen, ketoprofen, Celebrex, Celebrex, ibuprofen, düşük dozlarda) kaçınmalısınız. Eğer birlikte uygulanması gerekli ise, hastalar yakından toksisite, özellikle çalışma, toksisite ve gastrointestinal toksisite açısından izlenmelidir. Uzun yarı ömrü olan non-steroid kullanımı ile ilgili, eğer hastalık mesane kasları yönetim önerilir sonra 2 gün önce en az 5 gün için NSAID doz stopaj verilerin olmaması.

Kaynaklar
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Pemetrexed Disodium

Jenerik adı: pemetrexed

Marka adı: Alimta

Eşdeğer ilaçlar: Pemetrexed, PEMEtrexed

Voltaren

Jenerik adı: diclofenac

Marka adı: Voltaren, Voltaren-XR, also Cambia, Cataflam, Zipsor, Zorvolex, Dyloject, Cambia

Eşdeğer ilaçlar: yok

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